Several mathematical methods support the analysis of network structured data and help to uncover important properties of networks. The ranking of network elements (vertices and edges) using centralities is such a method and we have developed CentiBiN (CENTralities In BIological Networks) to assist the centrality based analysis of networks. CentiBiN is a tool for the computation and comparison of different network centralities. It is used in our ongoing work on evaluating centrality measures for specific biological networks.
B. H. Junker, D. Koschützki and F. Schreiber. Exploration of biological network centralities with CentiBiN. BMC Bioinformatics, 7:e219, 2006.