Equipment

Representative Publications

  • "Tropinone biosynthesis requires catalysis by a non-canonical type III polyketide synthase followed by P450-mediated ring closure." Bedewitz MA, Jones AD, D'Auria JC, Barry CS (2018). Nature Communications 9 (1), 5281. 
  • "Efficient synthesis of (S)-4-(1-methylpyrrolidin-2-yl)-3-oxobutanoate as the key intermediate for tropane alkaloid biosynthesis without racemization."Katakam NK, Seifert CW, D'Auria JC, Li G. (2018). Heterocycles (99).
  • "Improved synthesis of N-methylcadaverine.",Anderson K, Moaven S, Unruh DK, Cozzolino AF, D'Auria JC.(2018) Molecules (23) E1216.
  • "Tropane and granatane alkaloid biosynthesis: A Systematic analysis." Kim, N, Estrada, O, Chavez B, Stewart C, D'Auria JC (2016). Molecules 21(11), 1510-1535. doi:10.3390/molecules 21111510. 
  • "The last step in cocaine biosynthesis is catalyzed by a BAHD acyltransferase."Schmidt, G., Jirschitzka, J., Porta, T., Reichelt, M., Luck, K., Pardo-Torre, J., Dolke, F., Varesio, E., Hopfgartner, G., Gershenzon, J., D'Auria, J. (2015).Plant Physiology, 16(1), 89-101. doi:10.1104/pp.114.248187.
  • "Influence of medium and elicitors on the production of cocaine, amino acids and phytohormones by Erythroxylum coca calli.",Docimo T, Davis AJ, Luck K, Fellenberg C, Reichelt M, Phillips M, Gershenzon J, D'Auria JC.(2015) Plant Cell, Tissue and Organ Culture (PCTOC)doi: 10.1007/s11240-014-0660-8.
  • "Increasing the Pace of New Discoveries in Tropane Alkaloid Biosynthesis". Jan Jirschitzka, Franziska Dolke, John C. D'Auria,. In Nathalie Giglioli-Guivarc'h, editors : Advances In Botanical Research, Vol. 68,Burlington: Academic Press, 2013, pp. 39-72. ISBN: 978-0-12-408061-4.
  • "Selection and validation of reference genes for quantitative gene expression studies in Erythroxylum coca", Docimo, T., Schmidt, G., Luck, K., Delaney, S. K., D'Auria, J (2013).Faculty of 1000 Research,2:37. doi:10.3410/f1000research.2-37.v1.
  • "Learning from nature: new approaches to the metabolic engineering of plant defense pathways", Jirschitzka, J., Mattern, D. J.,Gershenzon, J., D'Auria, J. (2013).Current Opinion in Biotechnology,24(2),320-328. doi:10.1016/j.copbio.2012.10.014.
  • "The biosynthesis of hydroxycinnamoyl quinate esters and their role in the storage of cocaine in Erythroxylum coca." Pardo-Torre, J., Schmidt,G., Paetz, C., Reichelt, M., Schneider, B., Gershenzon, J.' D'Auria, J. (2013). Phytochemistry, 91, 177-186. doi:10.1016/j.phytochem.2012.09.009.
  • "The first step in the biosynthesis of cocaine in Erythroxylum coca: the characterization of arginine and ornithine decarboxylases.", Docimo, T., Reichelt, M., Schneider, B., Kunert, G., Gershenzon, J., D'Auria, J. ( 2012).Plant Molecular Biology, 78(6), 599-615. doi:10.1007/s11103-012-9886-1.
  • "Plant tropane alkaloid biosynthesis evolved independently in the Solanaceae and Erythroxylaceae.", Jirschitzka, J., Schmidt, G., Reichelt, M., Schneider, B., Gershenzon, J., D'Auria, J. (2012). Proceedings of the National Academy of Sciences of the United States of America, 109(26), 10304-10309. doi:10.1073/pnas.1200473109.
  • "Contribution of CoA ligases to benzenoid biosynthesis in Petunia flowers. ", Klempien, A.; Kaminaga, Y.; Qualley, A.; Nagegowda, D. A., Widhalm, J. R., Orlova, I., Shasany, A. K., Taguchi, G., Kish, C. M., Cooper, B. R., D'Auria, J., Rhodes, D., Pichersky, E., Dudareva, N. (2012). The Plant Cell, 24,2014-2030. doi:10.1105/tpc.112.097519.
  • "Evaluation of candidate reference genes for real-time quantitative PCR of plant samples using purified cDNA as template.", Phillips, M., D'Auria, J., Luck, K.; Gershenzon, J. (2009).Plant Molecular Biology Reporter, 27(3), 407-416. doi:10.1007/s11105-008-0072-1.
  • "The Arabidopsis thaliana type I isopentenyl diphosphate isomerases are targeted to multiple subcellular compartments and have overlapping functions in isoprenoid biosynthesis.", Phillips, M. A.; D'Auria, J., Gershenzon, J., Pichersky, E. (2008) The Plant Cell, 20(3), 677-696. doi:10.1105/tpc.107.053926.
  • "Characterization of a BAHD acyltransferase responsible for producing the green leaf volatile (Z)-3-hexen-1-yl acetate in Arabidopsis thaliana." D'Auria, J., Pichersky, E.,Schaub, A., Hansel, A., Gershenzon, J. (2007).The Plant Journal, 49(2), 194-207.
  • "Identification and characterization of the BAHD acyltransferase malonyl CoA: Anthocyanidin 5-O-glucoside-6''-O-malonyltransferase (At5MAT) in Arabidopsis thaliana."D'Auria, J., Reichelt, M., Luck, K., Svatos, A., Gershenzon, J. (2007).FEBS Letters, 581, 872-878.
  • "Characterization of seed-specific benzoyloxyglucosinolate mutations in Arabidopsis thaliana." Kliebenstein, D. J., D'Auria, J., Behere, A. S., Kim, J. H., Gunderson, K. L., Breen, J. N., Lee, G., Gershenzon, J., Last, R. L., Jander, G. (2007).The Plant Journal, 51(6), 1062-1076.
  • "Acyltransferases in plants: a good time to be BAHD." D'Auria, J. (2006). Current Opinion in Plant Biology, 9(3), 331-340.
  • "The secondary metabolism of Arabidopsis thaliana: growing like a weed." D'Auria, J., Gershenzon, J. (2005).Current Opinion in Plant Biology, 8(3), 308-316.
  • "An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense." Chen, F., D'Auria, J., Tholl, D., Ross, J. R., Gershenzon, J., Noel, J. P., Pichersky, E. (2003). An Arabidopsis thaliana gene for methylsalicylate biosynthesis, identified by a biochemical genomics approach, has a role in defense. The Plant Journal, 36(5), 577-588. Retrieved from ://000186532400001.
  • "Biosynthesis and emission of terpenoid volatiles from Arabidopsis flowers." Chen, F., Tholl, D., D'Auria, J., Farooq, A., Pichersky, E., Gershenzon, J. (2003). Biosynthesis and emission of terpenoid volatiles from Arabidopsis flowers. The Plant Cell, 15(2), 481-494. Retrieved from ://000181008700014.