Applied Chromosome Biology
The independent research group Applied Chromosome Biology (ACB) studies the genetic and epigenetic mechanisms of meiosis and gametogenesis, which are essential for genome stability and fertility. Meiosis and gametogenesis are very susceptible to climate change. Hence, we are especially interested in how conditions influence the above processes. Elucidating underlying mechanisms will allow us to harness sensitivity and enhance tolerance for crop improvement.
We use Arabidopsis as the model plant to address fundamental biological questions. Meanwhile, we also apply our knowledge on cereal crops and economic vegetables.
Our research is embedded in the department of Breeding Research, and we contribute to the IPK research theme FSP3 "Mechanisms of Reproduction".
Combining epigenomic, proteomic, and forward genetic approaches, we aim to understand how plants maintain genome stability and fertility during reproductive development, especially under climate change. Currently, we are working on the following topics:
- Identifying the role of epigenetic regulation in meiosis and gametogenesis
- Elucidating the mechanisms of unreduced gamete formation in plants
- Understanding the genetic and epigenetic basis of reproductive thermo-tolerance
Cheng J, Xu L, Bergér V, Bruckmann A, Yang C, Schubert V, Grasser K D, Schnittger A, Zheng B, Jiang H:
H3K9 demethylases IBM1 and JMJ27 are required for male meiosis in Arabidopsis thaliana. New Phytol. 235 (2022) 2252-2269. https://dx.doi.org/10.1111/nph.18286
Cheng J, Zhang G, Xu L, Liu C, Jiang H:
Altered H3K27 trimethylation contributes to flowering time variations in polyploid Arabidopsis thaliana ecotypes. J. Exp. Bot. 73 (2022) 1402-1414. https://dx.doi.org/10.1093/jxb/erab470
Piskorz E W, Xu L, Ma Y, Jiang H:
Double-haploid induction generates extensive differential DNA methylation in Arabidopsis. J. Exp. Bot. (2022) accepted. https://dx.doi.org/10.1093/jxb/erac397
Xu L, Cheng J, Jiang H:
Mutation of histone H3 serine 28 to alanine influences H3K27me3-mediated gene silencing in Arabidopsis. Plant Physiol. (2022) accepted. https://dx.doi.org/10.1093/plphys/kiac409
Yi J, Kradolfer D, Brownfield L, Ma Y, Piskorz E, Köhler C, Jiang H:
Meiocyte size is a determining factor for unreduced gamete formation in Arabidopsis thaliana. New Phytol. (2022) Epub ahead of print. https://dx.doi.org/10.1111/nph.18473
Zhong Z, Wang Y, Wang M, Yang F, Thomas Q A, Xue Y, Zhang Y, Liu W, Jami-Alahmadi Y, Xu L, Feng S, Marquardt S, Wohlschlegel J A, Ausin I, Jacobsen S E:
Histone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis. Nat. Commun. 13 (2022) 6970. https://dx.doi.org/10.1038/s41467-022-34648-0
Chandra J R:
Functional analysis of H3K9 demethylases in Arabidopsis. (Master Thesis) Kiel, Christian-Albrechts-Universität zu Kiel (2021) 43 pp.
Kuhlmann M, Jiang H, Catoni M, Johannes F:
Editorial: DNA methylation in plants associated with abiotic stress. Front. Plant Sci. 12 (2021) 778004. https://dx.doi.org/10.3389/fpls.2021.778004
Kuhlmann M, Jiang H, Catoni M, Johannes F (Eds.):
Front. Plant Sci., Frontiers Research Topic “DNA Methylation in Plants Associated with Abiotic Stress." Lausanne: Frontiers Media SA (2021)
Wang Y, Jiang H, Wang G:
PHERES1 controls endosperm gene imprinting and seed development. Trends Plant Sci. 25 (2020) 517-519. https://dx.doi.org/10.1016/j.tplants.2020.03.004
Wang Y, Zhong Z, Zhang Y, Xu L, Feng S, Rayatpisheh S, Wohlschlegel J A, Wang Z, Jacobsen S E, Ausin I:
NAP1-RELATED PROTEIN1 and 2 negatively regulate H2A.Z abundance in chromatin in Arabidopsis. Nat. Commun. 11 (2020) 2887. https://dx.doi.org/10.1038/s41467-020-16691-x
Xu L, Jiang H:
Writing and reading histone H3 lysine 9 methylation in Arabidopsis. Front. Plant Sci. 11 (2020) 452. https://dx.doi.org/10.3389/fpls.2020.00452
ldentifying the role of AHL22-complex in organ size regulation in Arabidopsis. (Master Thesis) Kiel, Christian-Albrechts-Universität zu Kiel (2020) 39 pp.
Flowering time variation in autopolyploid Arabidopsis thaliana. (Master Thesis) Göttingen, Georg-August-Universität Göttingen, Fakultät für Agrarwissenschaften (2019) 60 pp.
Wang G, Jiang H, Del Toro de León G, Martinez G, Köhler C:
Sequestration of a transposon-derived siRNA by a target mimic imprinted gene induces postzygotic reproductive isolation in Arabidopsis. Dev. Cell 46 (2018) 696-705. https://dx.doi.org/10.1016/j.devcel.2018.07.014